Unveiling the Future of Separation Science: A Conversation with Jennifer Kingston
The Spark of Innovation: Unlocking the Power of Technical Excellence
In the realm of chemical sciences, where attention to detail is paramount, Jennifer Kingston stands out as a beacon of technical excellence. Her journey, from a curious undergraduate to a director at AstraZeneca, is a testament to the power of passion and perseverance. But what truly sets her apart is her unwavering commitment to pushing the boundaries of separation science, a field that often goes unnoticed yet plays a pivotal role in drug discovery and development.
A Passion for Data and Discovery
As a group leader in separation science for oncology drug discovery, Kingston's days are filled with the meticulous analysis of lab data. Her sharp gaze and keen attention to detail are not just tools of the trade; they are the driving force behind her success. Yet, it is her ability to champion sustainable methods and establish innovative apprenticeship programs that truly sets her apart. In a world where technical excellence is highly sought after, Kingston's work is a shining example of how one can make a profound impact through both scientific prowess and a commitment to mentorship.
A Career Fueled by Curiosity
Kingston's journey began with a famous blue pill, which sparked her interest in drug development. After completing her undergraduate degree at the University of Liverpool, she dove headfirst into analytical chemistry at the National Rivers Authority. But it was her PhD on passive sampling techniques for organic pollutants at the University of Portsmouth that ignited her passion for drug development. The intellectual stimulation she sought was found in the serendipitous origin stories of drugs like Viagra, and she knew she had found her calling.
Challenging Chemistry: A Journey to Supercritical Fluid Chromatography
Kingston's career took a pivotal turn when she joined Pfizer and encountered Terry Berger, a pioneer in supercritical fluid chromatography (SFC). Berger's work transformed SFC into a more efficient and sustainable technique, and Kingston became an advocate for its adoption. Despite initial challenges in influencing her workplace, she successfully implemented SFC at Merck Sharp & Dohme and Novartis. Her arrival at AstraZeneca in 2014 marked a new chapter, as she brought the technology to existing Cambridge sites and planned its large-scale expansion at the Discovery Centre, which opened in 2021 as the company's largest UK research center.
From Apprentices to Scientists: Nurturing the Next Generation
One of Kingston's greatest achievements is the degree apprenticeship scheme, a three-year program hosted by the early oncology group. The scheme, which she pitched to senior management in 2016, has been a resounding success. More than 20 students have gone through the program, with the first now a chemistry teacher and another a senior-level scientist at AstraZeneca. The scheme not only benefits the organization by filling knowledge gaps and offering new perspectives but also empowers apprentices to become scientists in their own right.
The Future of Separation Science: A Vision for the Undruggable
As Kingston reflects on her journey, she is clear about her next steps. With AstraZeneca, she is building molecules that nobody thought they could build to treat diseases in ways that were once thought impossible. Her work is a testament to the power of curiosity and the potential for innovation in the field of separation science. As she continues to push the boundaries of what is possible, Kingston's impact on the field is sure to be felt for generations to come.
Jennifer Kingston's CV:
- Director, AstraZeneca: 2024–present
- Associate Director, AstraZeneca: 2015–2024
- Investigator III (Head of Analytical group at Novartis, Horsham), Novartis: 2007–2014
- Separation Scientist, Merck Sharp & Dohme: 2003–2006
- Separation Scientist, Pfizer: 2000–2002
- PhD in Analytical Science, University of Portsmouth: 1997–2000
- Analytical chemist, National Rivers Authority, 1989–1997
- BSc in Chemistry, University of Liverpool: 1986–1989
